刘汝萃,范书琴,张建全,等.鳕鱼肝油软胶囊增强小鼠免疫功能的研究[J].中国油脂,2018,43(4):.[LIU Rucui, FAN Shuqin, ZHANG Jianquan,etc.Enhancement of immune function of mice by cod liver oil soft capsule[J].China Oils and Fats,2018,43(4):.]
鳕鱼肝油软胶囊增强小鼠免疫功能的研究
Enhancement of immune function of mice by cod liver oil soft capsule
  
DOI:
中文关键词:  鳕鱼肝油  软胶囊  小鼠  免疫功能
英文关键词:cod liver oil  soft capsule  mice  immune function
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刘汝萃,范书琴,张建全,等  
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中文摘要:
      研究了鳕鱼肝油软胶囊增强小鼠的免疫功能。以鳕鱼肝油软胶囊0.042 、0.083 、0.250 g/kg3个剂量给予小鼠经口灌胃一个月,进行小鼠细胞免疫功能、体液免疫功能、单核-巨噬细胞功能及NK细胞活性测定。结果表明:0.250 g/kg组加ConA孔与不加ConA孔吸光度的差值、耳壳增重均显著高于对照组(玉米油组,下同)(P<0.05);0.250 g/kg组小鼠溶血空斑数及血清半数溶血值(HC50)极显著高于对照组(P<0.01);0.250 g/kg组小鼠吞噬指数a极显著高于对照组(P<0.01)。研究表明鳕鱼肝油软胶囊具有增强小鼠免疫功能。
英文摘要:
      The enhancement of the immune function of mice by cod liver oil soft capsule was studied. The mice were administered for a month with 0.042, 0.083, 0.250 g/kg dose of cod liver oil soft capsule, and the functions of mice cellular immunity, humoral immunity, mononuclear macrophage function and NK cell activity were determined. The results showed that the absorbance difference of 0.250 g/kg dose group with ConA hole or without ConA hole and concha weight gain were significantly higher than control group(P<0.05). The hemolytic plaque number, half hemolytic value(HC50)and phagocytic index were very significantly higher than control group(P<0.01). So cod liver oil soft capsule had the function of enhancing the immune function of mice.
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