| 谢亮亮1，李龙1，谢丹1，郑立友1，金俊2，金青哲2.4,4-二甲基甾醇生物活性研究进展[J].中国油脂,2024,49(7):.[XIE Liangliang1, LI Long1, XIE Dan1, ZHENG Liyou1, JIN Jun2, JIN Qingzhe2.Research progress on biological activity of 4,4-dimethylsterol[J].China Oils and Fats,2024,49(7):.] |
| 4,4-二甲基甾醇生物活性研究进展 |
| Research progress on biological activity of 4,4-dimethylsterol |
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| DOI： |
| 中文关键词: 4,4-二甲基甾醇 糖尿病 肥胖 生物活性 |
| 英文关键词:4,4-dimethylsterol diabetes mellitus obesity biological activity |
| 基金项目:安徽省重点研究与开发计划（202104a06020030）；安徽省自然科学基金（2308085MC111） |
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| 中文摘要: |
| 旨在为4,4-二甲基甾醇在功能食品、保健品和药品等领域的开发应用提供科学的理论参考，概述了4,4-二甲基甾醇的来源、提取与分离纯化方法、鉴定方法及吸收与代谢，在此基础上对4,4-二甲基甾醇的降血糖、抗炎、减肥降脂、抑菌、抗肿瘤及抗阿尔茨海默病等方面表现的潜在生物活性进行了归纳总结，并对目前存在的问题提出相应的对策。4,4-二甲基甾醇是一种重要的植物甾醇，具有多种生物活性，表现出较大的潜在应用价值。 |
| 英文摘要: |
| In order to provide scientific theoretical reference for the application of 4,4-dimethylsterol in functional food, health products and drugs,the source, method of extraction, isolation and purification, identification method, and absorption and metabolism of 4,4-dimethylsterol were outlined, then the potential bioactivities of 4,4-dimethylsterol in terms of hypoglycemic, anti-inflammation, weight loss and lipid lowering, bacteriostasis, anti-tumor and anti-Alzheimer′s disease were summarized, and the corresponding countermeasures were proposed for the current problems. 4,4-Dimethylsterol is a kind of important phytosterol with a variety of bioactivities and shows a large potential application value. |
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