唐丹丹1,孙宸婧1,顾嘉文1,林银山1,钱秀娟1,董维亮1,2.产棕榈油酸酵母提取液的活性分析[J].中国油脂,2025,50(9):.[TANG Dandan1, SUN Chenjing1, GU Jiawen1, LIN Yinshan1, QIAN Xiujuan1, DONG Weiliang1,2.Activity analysis of extracts from palmitoleic acid-producing yeast[J].China Oils and Fats,2025,50(9):.]
产棕榈油酸酵母提取液的活性分析
Activity analysis of extracts from palmitoleic acid-producing yeast
  
DOI:10.19902/j.cnki.zgyz.1003-7969.240284
中文关键词:  棕榈油酸  酵母提取液  抗氧化活性  酪氨酸酶抑制活性
英文关键词:palmitoleic acid  yeast extract  antioxidant activity  tyrosinase inhibitory activity
基金项目:国家重点研发计划(2021YFC2101500);国家级大学生创新创业训练计划项目(202310291080Z)
作者单位
唐丹丹1,孙宸婧1,顾嘉文1,林银山1,钱秀娟1,董维亮1,2 1.南京工业大学 生物与制药工程学院南京 211800 2.南京工业大学 材料化学工程国家重点实验室南京 211800 
Author NameAffiliation
TANG Dandan1, SUN Chenjing1, GU Jiawen1, LIN Yinshan1, QIAN Xiujuan1, DONG Weiliang1,2 1.College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing 211800, China
2.State Key Laboratory of Materials-Oriented Chemical Engineering, Nanjing Tech University, Nanjing 211800, China 
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中文摘要:
      为探究富含棕榈油酸(POA)的酵母提取液在化妆品中的应用潜力和价值,以具有POA合成能力的产油酵母Scheffersomyces segobiensis DSM 27193及其重组菌株SS-12为研究对象,检测二者油脂及POA含量,并测定了S. segobiensis DSM 27193和SS-12酵母提取液的多酚含量、抗氧化活性和酪氨酸酶抑制活性。结果表明:S. segobiensis DSM 27193及其重组菌株SS-12两株酵母油脂含量分别为14.72%和34.35%,POA在油脂中的占比分别为12.03%和16.00%;两株酵母提取液的多酚含量最高分别可达(3 269±56)μg/mL和(3 546±268)μg/mL,对DPPH自由基的清除率最高分别可达71.70%和77.38%,还原力最高分别可达0.459和0.578,对酪氨酸酶抑制率最高分别可达91.25%和99.37%。综上,两种酵母提取液均具有良好的抗氧化活性和酪氨酸酶抑制活性,在化妆品领域具有优良的应用前景。
英文摘要:
      To investigate the potential and value of palmitoleic acid (POA)-rich yeast extracts for cosmetic applications, the oleaginous yeast Scheffersomyces segobiensis DSM 27193 (with POA synthesis ability) and its modified strain SS-12 were used as research subjects, their oils and POA contents were analyzed, and the polyphenol content, antioxidant activity, and tyrosinase inhibitory activity of the yeast extracts of S. segobiensis DSM 27193 and SS-12 were determined. The results showed that the oils contents of S. segobiensis DSM 27193 and SS-12 were 14.72% and 34.35%, respectively, and the percentages of POA in the oils were 12.03% and 16.00%, respectively. The polyphenol contents of the two yeast extracts could reach up to (3 269±56)μg/mL and (3 546±268)μg/mL, the scavenging rate of DPPH radicals could reach up to 71.70% and 77.38%, the reducing power could reach up to 0.459 and 0.578, and the inhibition rate of tyrosinase could reach up to 91.25% and 99.37%, respectively. In conclusion, both yeast extracts have good antioxidant activity and tyrosinase inhibitory activity, and have an excellent application prospect in the field of cosmetics.
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