| 杨灿1, 胡二坤2, 侯丽芬2, 杨海潮3, 张傲涵4, 高怡寒1,
赵静5，潘丽4，辛志华4, 关策4, 王收4.紫荆花花色苷脂质体的构建及其抗氧化活性研究[J].中国油脂,2026,51(4):.[YANG Can1, HU Erkun2, HOU Lifen2, YANG Haichao3, ZHANG Aohan4,
GAO Yihan1, ZHAO Jing5, PAN Li4, XIN Zhihua4, GUAN Ce4, WANG Shou4.Preparation and antioxidant activity of bauhinia anthocyanin-loaded liposomes[J].China Oils and Fats,2026,51(4):.] |
| 紫荆花花色苷脂质体的构建及其抗氧化活性研究 |
| Preparation and antioxidant activity of bauhinia anthocyanin-loaded liposomes |
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| DOI：10.19902/j.cnki.zgyz.1003-7969.250273 |
| 中文关键词: 紫荆花花色苷 脂质体 构建 抗氧化活性 |
| 英文关键词:bauhinia anthocyanin liposomes preparation antioxidant activity |
| 基金项目:国家自然科学基金青年基金项目（32001738）；河南工业大学“双一流”本科生科技创新能力提升专项（HN-HautFood IAEG-029）；大学生创新训练计划项目（202510463010，202510463106）；河南工业大学小麦和玉米深加工国家工程研究中心开放课题（NL2025010）；河南省自然科学基金面上项目（262300421438） |
| 作者 | 单位 | | 杨灿1, 胡二坤2, 侯丽芬2, 杨海潮3, 张傲涵4, 高怡寒1,
赵静5，潘丽4，辛志华4, 关策4, 王收4 | 1.河南工业大学 国际教育学院,郑州 450001； 2.河南职业技术学院 食品工程学院,郑州 450000；
3.郑州顺安机电设备有限公司,郑州 450000； 4.河南工业大学 小麦和玉米深加工国家工程
研究中心,郑州 450001
5.河南工业大学 教师教学发展中心,郑州 450001 |
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| Author Name | Affiliation | | YANG Can1, HU Erkun2, HOU Lifen2, YANG Haichao3, ZHANG Aohan4,
GAO Yihan1, ZHAO Jing5, PAN Li4, XIN Zhihua4, GUAN Ce4, WANG Shou4 | 1.College of International Education, Henan University of Technology, Zhengzhou 450001, China；
2.Department of Food Engineering, Henan Polytechnic, Zhengzhou 450000, China； 3.Zhengzhou
Shun′an Electromechanical Equipment Co. , Ltd. , Zhengzhou 450000, China； 4.National Engineering
Research Center of Wheat and Corn Further Processing, Henan University of Technology,
Zhengzhou 450001, China
5.Center for Teaching and Learning Development,
Henan University of Technology, Zhengzhou 450001, China |
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| 中文摘要: |
| 为了提高紫荆花花色苷的稳定性和抗氧化活性，以大豆卵磷脂为主要膜材制备花色苷脂质体，对其粒径、多分散性指数(PDI)和Zeta电位进行测定，采用透射电子显微镜观察微观结构，并进行结构表征，同时测定了其抗氧化活性。结果表明：紫荆花花色苷脂质体的包封率为(39.37±152)%，平均粒径为(126.97±2.05)nm，PDI为0.37±0.02，Zeta电位为(-16.8±0.9)mV，表明紫荆花脂质体囊泡较小，为纳米级，且分布均匀；紫荆花花色苷脂质体呈规则的球形;结构表征结果说明紫荆花花色苷被脂质体成功包埋;通过DPPH自由基、ABTS+自由基的清除能力以及还原能力测定，得到抗氧化活性的强弱顺序为紫荆花花色苷脂质体＞紫荆花花色苷纯化物＞紫荆花花色苷粗提物。综上，脂质体包埋对紫荆花花色苷起到了一定的保护作用，且增强了其抗氧化活性。 |
| 英文摘要: |
| In order to improve the stability and antioxidant activity of bauhinia anthocyanin, soybean phosphatidylcholine was used as the main membrane material to prepare bauhinia anthocyanin-loaded liposomes. The particle size, polydispersity index (PDI) and Zeta potential of bauhinia anthocyanin-loaded liposomes were measured, while their microstructure was observed using a transmission electron microscope and its structure was characterized, as well as the antioxidant activity was determined. The results showed that the encapsulation efficiency of bauhinia anthocyanin-loaded liposomes was (39.37±1.52)%, the average particle size was (126.97±2.05) nm with the PDI of 0.37±0.02, and the Zeta potential was (-16.8±0.9) mV, which revealed that the vesicles of bauhinia anthocyanin-loaded liposomes were small, nanoscale and evenly distributed. The bauhinia anthocyanin-loaded liposomes presented regular spherical shape. The results of structural characterization showed that the successful encapsulation of bauhinia anthocyanin into liposomes. Based on the determinations of scavenging capacities of DPPH and ABTS+ free radicals, as well as the reducing capacity, the order of antioxidant activity was as follows: bauhinia anthocyanin-loaded liposomes>purified bauhinia anthocyanin > crude bauhinia anthocyanin. In summary, the encapsulation by liposomes can protect the bauhinia anthocyanin and improves its antioxidant activity. |
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