| 王俊，王淑娜，许新德，等.Omega-3脂肪酸磷脂制备方法综述[J].中国油脂,2018,43(8):.[WANG Jun，WANG Shuna,XU Xinde，etc.Review on preparation methods of Omega-3 fatty acids phospholipids[J].China Oils and Fats,2018,43(8):.] |
| Omega-3脂肪酸磷脂制备方法综述 |
| Review on preparation methods of Omega-3 fatty acids phospholipids |
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| DOI： |
| 中文关键词: Omega-3脂肪酸 磷脂 制备 |
| 英文关键词:Omega-3 fatty acid phospholipids preparation |
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| 摘要点击次数: 1275 |
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| 中文摘要: |
| Omega-3脂肪酸磷脂生理功能明确，生物利用度高，在医药、保健品领域具有巨大的市场潜力，其制备方法是全球磷脂研究开发的新动向。综述了目前Omega-3脂肪酸磷脂的制备方法，包括天然提取法、酶促转化法、化学合成法及微生物发酵法。天然提取法是最早获得Omega-3脂肪酸磷脂产品的方法，主要包括溶剂萃取法、膜分离法、柱层析法和盐沉淀法；酶促转化法主要包括酶促酯交换法和酶促酯化法，是目前Omega-3脂肪酸磷脂合成效率最高、最常用的方法；化学合成法及微生物发酵法处于初步研究阶段，为Omega-3脂肪酸磷脂的制备提供了新的思路。 |
| 英文摘要: |
| Omega-3 fatty acids phospholipids have clear physiological function and high bioavailability, its market potential is huge in the fields of medicine and nutritional products, and more and more researches are focusing on the preparation methods of Omega-3 fatty acids phospholipids. The preparation methods of Omega-3 fatty acids phospholipids were reviewed, including natural extraction, enzymatic catalysis conversion, chemical synthesis and microbial fermentation. Omega-3 fatty acids phospholipids products were firstly prepared by natural extraction method, including solvent extraction, membrane separation, column chromatography and salt precipitation. Enzymatic catalysis conversion was the most common method with the highest efficiency currently, including enzymatic transesterification and enzymatic esterification. Chemical synthesis and microbial fermentation provided new preparation ways to obtain Omega-3 fatty acids phospholipids which were in preliminary study stage and required further research. |
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