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| α-亚麻酸体内转化为二十碳五烯酸和二十二碳六烯酸的研究进展 |
| Review on endogenous conversion of α--linolenic acid to EPA and DHA |
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| DOI： |
| 中文关键词: α-亚麻酸 n-3长链多不饱和脂肪酸 二十二碳六烯酸 二十碳五烯酸 |
| 英文关键词:α-linolenic acid n-3 long chain polyunsaturated fatty acid docosahexaenoic acid eicosapntemacnioc acid |
| 基金项目: |
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| 中文摘要: |
| 水产品是二十碳五烯酸（EPA）和二十二碳六烯酸（DHA）等n-3长链多不饱和脂肪酸（n-3 LCPUFA）的主要膳食来源。我国广大内陆地区居民膳食中水产品消费量很低，EPA和DHA的摄入量远低于推荐量。α-亚麻酸（ALA）是我国居民膳食中最主要的n-3多不饱和脂肪酸（n-3 PUFA），其在体内可以转化为n-3 LCPUFA。近来的研究表明，ALA转化能力受ALA摄入状况及人群生理差异影响，其中新生儿的内源转化效率较低，而育龄期妇女和鱼类低消费人群的转化效率较高，提示膳食ALA对改善这些人群的脂肪酸营养状况有着重要的意义。通过对相关方面的研究进行综述，以期更加客观、全面地认识α-亚麻酸的作用。 |
| 英文摘要: |
| Aquatic products are the main dietary sources of n-3 long chain polyunsaturated fatty acid（n-3 LCPUFA），such as eicosapentaenoic acid （EPA） and docosahexaenoic acid （DHA）. The consumption amount of aquatic products is low in residents dietary of most inland areas in China，and the intake amounts of EPA and DHA are far lower than the recommendation in these areas. α-linolenic acid （ALA） is the main n-3 PUFA in Chinese dietary pattern and it can be converted to n-3 LCPUFA in vivo. Recent studies indicate that the conversion capacity of ALA is affected by the intake status of ALA and population physiological difference，in which the endogenous conversion capacity is lower in neonates whereas it is higher in women of childbearing age and population with low fish consumption，showing that the dietary ALA is more important to improve fatty acids nutritional status for these population. Related researches were reviewed to get more objective and comprehensive understanding of the effect of ALA on human health. |
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