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| Effect of dietary docosahexaenoic acid (DHA) in phospholipids and triglycerides on DHA level in body tissues of infant mice |
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| KeyWord:docosahexaenoic acid (DHA) n-3 PUFAs deficiency infant mice lactation |
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| Abstract: |
| The effect of dietary docosahexaenoic acid (DHA) in phospholipids and triglycerides during lactation on fatty acid composition and DHA level in body tissues of infant mice was investigated. The n-3 polyunsaturated fatty acids (n-3 PUFAs) deficient feeds were given to pregnant mice during the gestation period, after delivery the feeds would be changed into n-3 deficient (deficient group), DHA-TG (DHA-TG group) and DHA-PL (DHA-PL group) for 3 weeks until weaning. The fatty acid composition and DHA levels in total lipid of cerebral cortex, liver, serum and erythrocytes of infant mice were measured. Compared with the deficient group, the DHA and n-3 PUFAs contents in the DHA-TG and DHA-PL groups were significantly increased, docosahexaenoic acid (DPA), arachidonic acid (AA) and the ratio of n-6 PUFAs to n-3 PUFAs were obviously decreased. The levels of DHA in total lipid of cerebral cortex and erythrocytes of infant mice in DHA-PL group were significantly higher than those in DHA-TG group, but there was no significant difference in the levels of DHA in total lipid of liver and serum. Given DHA-TG and DHA-PL during lactation could significantly improve DHA levels in infant’s body tissues, in which DHA-PL had a better effect on cerebral cortex and erythrocytes. |
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