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Effects of alpha-tocopherol succinate on balance of NK cells and ApoE gene expression in excessive movement mice |
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KeyWord:alpha-tocopherol succinic excessive movement NK cell ApoE gene |
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Abstract: |
By alpha-tocopherol succinic acting on the excessive movement mice, the effects of it on balance of NK cells and ApoE gene expression in mice were investigated. The results showed that the alpha tocopherol succinic to overcome immunosuppressive phenomenon of excessive movement mice had significant effect, with CD3+, CD16+ ,CD56+ cells factor decreasing extremely significant (P<0.01),and ApoE mRNA and ApoE protein expression increasing extremely significant (P<0.01). Different concentrations of alpha-tocopherol succinic had certain different effects. The balance of NK cells and the ApoE expression of high concentration group was obviously better than that of low concentration group (P<0.05). |
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