| In order to investigate the effects of ω-3PUFAs on the myocardial cell metabolism and the changes of serum T-SOD, MDA, blood lactate, LDH, IL-4, IL-6 and INF-纬 in rats, the SD rats were divided into sedentary control (Rc) group, exercise control (Mc) group, low dose ω-3PUFAs gavage(G1) group, medium dose ω-3PUFAs gavage(G2) group and high dose ω-3PUFAs gavage(G3) group, and a compound ω-3PUFAs intervention experiment by treadmill exercise for eight weeks was carried out. The results showed that the contents of high-energy phosphate compounds in experimental group were higher than those in Mc group. Serum T-SOD activity in experimental group showed an upward trend, while MDA content showed a downward trend, and G1 group had a significant difference with Mc group (P<0.05), G2 and G3 groups had highly significant differences with Mc group (P<0.01). Blood lactate levels in experimental group showed a downward trend. G1 and G2 groups had significant differences with Mc group (P<0.05), and G3 group had highly significant differences with Mc group(P<0.01). LDH content in experimental group showed an upward trend, and it was positively correlated with ω-3 PUFAs dose. Serum IL-4, IL-6, INF-γ levels in experimental group rats were lower than those in Mc group. Different doses of ω-3 PUFAs had intervention on the myocardial cell metabolism, antioxidant capacity and serum IL-4, IL-6, INF-γ in rats. |
