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| Effects of Ophiopogon japonicus seed oil on antioxidant activity of liver in rats after exhaustive exercise |
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| KeyWord:Ophiopogon japonicus seed oil exhaustive exercise rat liver antioxidation |
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| Abstract: |
| In order to study the effect of Ophiopogon japonicus seed oil on the antioxidant activity of liver in rats after exhaustive exercise, the rats after exhaustive exercise were treated with Ophiopogon japonicus seed oil by intragastric administration. Fifty healthy rats were randomly divided into normal group, model group, low dose group, middle dose group and high dose group. Except the normal group, the other four groups of rats were treated with 9% D-galactosamine (D-gal) solution to induce liver injury. Low dose, middle dose and high dose groups of rats were treated with Ophiopogon japonicus seed oil. The results showed that the liver index of model group decreased significantly than that of normal group (P＜0.05), but there was no significant difference among normal group and low, middle and high dose groups (P＞0.05). The content of MDA in model group was significantly higher than that in normal group (P＜0.05), and it was higher in middle dose and high dose groups than that in normal group, but the difference was not significant (P＞0.05). Compared with normal group, the SOD activity of model group was significantly decreased (P＜0.05), but each dose group had no significant difference (P＞0.05). So Ophiopogon japonicus seed oil had strong antioxidant activity on liver in rats after exhaustive exercise. |
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