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| 欧李果籽油对力竭运动后大鼠肝组织抗氧化能力的影响 |
| Effects of Ophiopogon japonicus seed oil on antioxidant activity of liver in rats after exhaustive exercise |
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| DOI： |
| 中文关键词: 欧李果籽油 力竭运动 大鼠 肝组织 抗氧化 |
| 英文关键词:Ophiopogon japonicus seed oil exhaustive exercise rat liver antioxidation |
| 基金项目: |
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| 中文摘要: |
| 为研究欧李果籽油对大鼠力竭运动后肝组织抗氧化能力的影响，对力竭运动后的大鼠进行欧李果籽油灌胃处理。将50只健康SD大鼠随机分为正常组、模型组、低剂量组、中剂量组、高剂量组。除正常组外，其余4组均被灌胃9%D-gal溶液诱导肝组织损伤，低剂量组、中剂量组和高剂量组的大鼠灌胃欧李果籽油。结果表明：模型组与正常组相比，大鼠的肝脏指数显著下降 (P＜005)，而低、中、高剂量组与正常组相比无显著变化 (P＞0.05)；模型组与正常组相比，MDA含量显著增加(P＜0.05)，中、高剂量组MDA含量比正常组高但差异不显著 (P＞0.05)；与正常组相比，模型组的SOD活性显著下降 (P＜0.05)，而各剂量组无显著变化 (P＞0.05)。由此可知，欧李果籽油在大鼠力竭运动后对肝组织具有较强的抗氧化能力。 |
| 英文摘要: |
| In order to study the effect of Ophiopogon japonicus seed oil on the antioxidant activity of liver in rats after exhaustive exercise, the rats after exhaustive exercise were treated with Ophiopogon japonicus seed oil by intragastric administration. Fifty healthy rats were randomly divided into normal group, model group, low dose group, middle dose group and high dose group. Except the normal group, the other four groups of rats were treated with 9% D-galactosamine (D-gal) solution to induce liver injury. Low dose, middle dose and high dose groups of rats were treated with Ophiopogon japonicus seed oil. The results showed that the liver index of model group decreased significantly than that of normal group (P＜0.05), but there was no significant difference among normal group and low, middle and high dose groups (P＞0.05). The content of MDA in model group was significantly higher than that in normal group (P＜0.05), and it was higher in middle dose and high dose groups than that in normal group, but the difference was not significant (P＞0.05). Compared with normal group, the SOD activity of model group was significantly decreased (P＜0.05), but each dose group had no significant difference (P＞0.05). So Ophiopogon japonicus seed oil had strong antioxidant activity on liver in rats after exhaustive exercise. |
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