|
| Treatment and relief effect of fish oil diet on dry eye disease in mice |
| |
| DOI： |
| KeyWord:fish oil dry eye disease DHA |
| FundProject: |
|
| Hits: 1416 |
| Download times: 478 |
| Abstract: |
| The treatment and relief effect of fish oil diet on dry eye disease in mice was studied. BALB/c mice with dry eye disease induced by benzalkonium chloride were randomly divided into control group (palm oil instead of fish oil) and fish oil dietary group, and the tear secretion and tear film rupture time of these two groups of mice were measured before and after feeding for 14 d. The mice were executed after 14 d, glands on the peripheral eye was taken, and DHA content was examined by GC. The results showed that compared with mice before feeding, tear secretion increased and tear film rupture time prolonged (P＜0.05) in fish oil dietary groupthe , and these changes in control group were not obvious(P＞0.05). Compared with control group, tear secretion of fish oil dietary group increased and tear film rupture time prolonged (P＜0.05) after feeding for 14 d. And the DHA content in the periocular glands of fish oil dietary group was significantly higher than that of control group (P<0.01). High DHA dietary could relieve dry eye disease symptom of mice induced by benzalkonium chloride, and it may be related to the supply of DHA in peri ocular gland. |
| View full text View/Add Comment Download reader |
| Close |
|
|
|
