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Optimization of preparation of conjugated linoleic acid from safflower seed oil by alkali isomerization using response surface methodology
  
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KeyWord:safflower seed oil  conjugated linoleic acid  alkali isomerization method  response surface methodology
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ZHANG Hongyu, WANG Shuping, JIN Tianyou，etc  
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Abstract:
      With Xinjiang high quality safflower seed oil as raw material, conjugated linoleic acid (CLA) was prepared by alkali isomerization method. The effects of reaction temperature, reaction time, dosage of PEG-400 and dosage of Fe(OH)3 on the conversion rate of CLA were studied by single factor experiment, at the same time the response surface methodology was used to optimize the preparation process. The results showed that when the mass of safflower seed oil was 20 g, the optimal preparation conditions of CLA from safflower seed oil by alkali isomerization were obtained as follows: using PEG-400 as solvent and Fe(OH)3 as catalyst, reaction t
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