The extraction process of total flavonoids from Persea americana Mill. meal was optimized by single factor experiment and response surface methodology, and its inhibitory effect on α-glucosidase activity was studied. The results showed that the optimal extraction conditions of total flavonoids from Persea americana Mill. meal were obtained as follows: extraction temperature 65?℃,extraction time 27 min, volume fraction of ethanol 60%, ratio of liquid to material 30∶?1 and extraction times once. Under the optimal conditions, the yield of total flavonoids reached 9.25%. The total flavonoids extract of Persea americana Mill. meal had a good inhibitory effect on α-glucosidase activity. |