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| Effect of fish oil soft capsule on memory improvement |
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| KeyWord:fish oil soft capsule memory improvement water maze test step-through test step-down test |
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| Abstract: |
| The effect of fish oil soft capsule on memory improvement was studied. 120 male Kunming mice of SPF were randomly divided into four groups: control group and low-, middle- and high-dose groups, and each group was administrated daily with fish oil soft capsule content 0, 0.075, 0.150, 0450 g/kg respectively for 30 d. Then the water maze test, step-through test and step-down test were carried out. The results showed that in water maze test, the time and errors reaching the final point of mice in each dose group were less than that in control group, and high-dose group was significantly different from control group (P＜0.05). In the step-through test, the number of animals entering the darkroom in low-and middle-dose groups were not significantly different from that in control group(P＞0.05), while for high-dose group, it was significantly different from that in control group(P＜005). In the step-down test, the step-down latency of mice during training in each dose group was not significantly different from that in control group (P＞0.05), and the step-down latency of mice during test in high-dose group was significantly different from that in control group (P＜0.05). So fish oil soft capsule had function of improving memory improvement. |
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