| The blood lipid-lowering effect of germinated brown rice bran (GBRB)was researched by studying the effect of GBRB on blood lipid metabolism in high-fat diet-fed rats. Fifty male SD rats were randomly and averagely divided into five groups. Rats in control group were fed with ordinary feed. Rats in high fat diet group were fed with high-fat feed. Rats in three dose groups were fed with high-fat feed with the addition of 30%, 20% and 10% of GBRB respectively. After feeding for 83 d, femoral artery blood of rats was taken and the concentrations of total-cholesterol (TC), triglyceride (TG), high density lipoprotein-cholesterol (HDL-C)and low density lipoprotein-cholesterol (LDL-C)were tested. In addition, the body fat rate was calculated. The results showed that after taking GBRB, there were no significant effects on body fat rate and normal growth of rats. In high, medium and low dose groups, the concentration of TC and LDL-C were significantly lower than those in high fat diet group (P<0.05). In high dose group, the concentration of TG was significantly lower than that in high fat diet group (P<0.05), though medium and low dose groups had less effect on TG level. GBRB could significantly decrease the contents of TC, TG and LDL-C of high fat diet rats, which indicated that GBRB had a blood lipid-lowering effect. |
