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| 花生粕纳豆杆菌发酵物对衰老雌鼠生长发育及抗氧化活性的影响 |
| Effects of peanut meal fermented by Bacillus natto on growth performance and antioxidant activity of aging female rats |
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| DOI： |
| 中文关键词: 花生粕 纳豆杆菌 发酵 衰老 生长发育 抗氧化活性 |
| 英文关键词:peanut meal Bacillus natto fermentation aging growth performance antioxidant activity |
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| 中文摘要: |
| 应用D-半乳糖建立大鼠衰老模型，探究花生粕纳豆杆菌发酵物（HFW）对衰老雌鼠生长发育及抗氧化活性的影响。结果表明：衰老模型组大鼠血清SOD活性明显低于正常对照组（P＜0.05），MDA含量明显高于正常对照组（P＜0.05），说明造模成功。试验期间，中、高剂量HFW组大鼠平均体重分别增加7.99%、12.18%。各组大鼠血脂酶含量无统计学差异（P>0.05），表明试验剂量的HFW对大鼠肝脏无损伤。与衰老模型组比较，HFW各组的TC、TG及LDL含量均表现为降低的趋势（P＜0.05），而HDL含量呈现升高的趋势（P＜0.05）；高剂量HFW组大鼠SOD活性明显升高（P＜0.05），中、高剂量HFW组大鼠MDA含量明显降低（P＜0.05）；且中、高剂量HFW组大鼠的胸腺指数明显高于衰老模型组（P＜0.05）。一定剂量的HFW可有效改善衰老引起的大鼠体重下降、血脂代谢异常等，提高抗氧化活性。 |
| 英文摘要: |
| The effects of fermentation product of peanut meal by Bacillus natto on growth performance and antioxidant activity of aging female rats induced by D-galactose were investigated. The results showed that the serum SOD activity of rats in aging model group was significantly lower than those in normal control group(P＜0.05), and the content of MDA was significantly higher than those in normal control group(P＜0.05), indicating that the model was successful. During the experiment, the average body weight of rats in middle and high dose groups increased by 7.99% and 12.18% respectively. There was no significant difference in serum lipid enzyme among rats in each group (P>0.05), indicating that the experimental dose of HFW had no obvious damage to the liver.Compared with the aging model group, the contents of TC,TG and LDL in each HFW group decreased significantly(P<0.05), and the content of HDL increased significantly(P<0.05). The SOD activity in middle and high dose groups increased significantly(P<0.05), and the content of MDA decreased significantly(P<0.05).The middle and high dose groups had a significant increase in thymus index of rats(P＜0.05). A certain dose of HFW had a significant improvement in the body weight loss and dyslipidemia, and increased antioxidant activity in aging rats. |
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