Omega-3 fatty acids phospholipids have clear physiological function and high bioavailability, its market potential is huge in the fields of medicine and nutritional products, and more and more researches are focusing on the preparation methods of Omega-3 fatty acids phospholipids. The preparation methods of Omega-3 fatty acids phospholipids were reviewed, including natural extraction, enzymatic catalysis conversion, chemical synthesis and microbial fermentation. Omega-3 fatty acids phospholipids products were firstly prepared by natural extraction method, including solvent extraction, membrane separation, column chromatography and salt precipitation. Enzymatic catalysis conversion was the most common method with the highest efficiency currently, including enzymatic transesterification and enzymatic esterification. Chemical synthesis and microbial fermentation provided new preparation ways to obtain Omega-3 fatty acids phospholipids which were in preliminary study stage and required further research. |