| The optimal technology of ultrasound-assisted extraction of sunflower seed flavonoids was studied. The ultrasonic power, extraction temperature, liquid-material ratio and extraction time were selected as factors by single factor experiment, and the process parameters of extraction of flavonoids from sunflower seed meal were optimized by response surface methodology with Box-Behnken design. The results showed that the optimal extraction parameters of flavonoids from sunflower seed meal were obtained as follows: ultrasonic power 120 W, extraction temperature 64?℃, liquid-material ratio 33∶?1 and extraction time 28 min. Under these conditions, the sunflower seed flavonoids yield was 1.91%. The IC50 of sunflower seed flavonoids on DPPH· was 0.09 mg/mL, which was better than that of food antioxidant BHT（the IC50 was 0.11 mg/mL）. Compared with the traditional Soxhlet extraction method, ultrasound-assisted extraction of sunflower seed flavonoids had the advantages of short time, energy saving and high yield. |
