| In order to study the effect of ethanol extract of Acanthopanax senticosus seed on the anti-fatigue of mice, forty mice were randomly divided into control group, low-dose group, medium-dose group and high-dose group. The mice were administrated once a day with low, medium and high doses of ethanol extract, and twice swimming exercises a day for seven weeks. The weight, contents of myoglycogen, hepatoglycogen, lactic acid (LAC), blood urea nitrogen (BUN) and activities of superoxide dismutase (SOD) and lactate dehydrogenase (LDH) of mice were determined.The results showed that compared with the control group, ethanol extract had no effect on the weight of mice, and could increase the swimming exhaustion time, myoglycogen, hepatoglycogen, SOD and LDH levels in the body, and reduce the contents of LAC and BUN in the body. The higher the ethanol extract of Acanthopanax senticosus seed dose, the more the obvious effect.The study indicated that the ethanol extract of Acanthopanax senticosus seed had a good effect on anti-fatigue of the body. |
