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Role of lipidomics in early diagnosis and therapy of diabetes and its complications
  
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KeyWord:lipidomics  diabetes  complications  drug  biomarker
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ZHANG Yiren，LI Xiaojing，LIU Ruijie  
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Abstract:
      Diabetes may occur with no symptoms or some non-obvious symptoms, such as mild fatigue, malaise and thirst. The diagnostic criteria for diabetes is only blood glucose, which is relatively single. In addition, the changes of the glycemic index in patients in the early stage of diabetes are not obvious until serious complications have arisen. With the development of lipidomics, more comprehensive and accurate assessment criteria for diagnosis and treatment effect of diabetes are established via determining and comparing the plasma lipid composition of diabetics and healthy individuals. The role of lipidomics in early diagnosis and therapy of diabetes and its complications was summarized. Moreover, the diagnostic biomarkers of diabetes and its complications and the effect of dietary structure and drugs on the type and content of biomarker were also summarized.
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