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| 支链脂肪酸的来源与功能研究进展 |
| Progress in source and function of branched-chain fatty acids |
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| DOI： |
| 中文关键词: 支链脂肪酸 脂肪酸 母乳脂肪 新生儿坏死性小肠结肠炎 |
| 英文关键词:branched-chain fatty acid fatty acid breast milk fat neonatal necrotizing enterocolitis. |
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| 中文摘要: |
| 支链脂肪酸主要包括单支链脂肪酸和多支链脂肪酸，多存在于人体皮肤及其分泌物、微生物细胞膜、乳制品及肉制品中。近年来的研究表明，支链脂肪酸对乳腺癌细胞、前列腺癌细胞和膀胱癌细胞等具有潜在抑制作用，此外，支链脂肪酸还有抑制新生儿坏死性小肠结肠炎发病率等抗炎作用。进一步对各种食物以及人体各组织中的支链脂肪酸进行检测分析，并对支链脂肪酸结构功能与作用机理进行深入研究，是目前支链脂肪酸研究的重要方向。 |
| 英文摘要: |
| Branched-chain fatty acids (BCFA) mainly include mono-branched-chain fatty acids and multi-branched-chain fatty acids, which are found in human skin and secretions, microbial cell membranes, and dairy products and meat products. Recent studies have shown that branched-chain fatty acids have potential inhibitory effects on cancer cells such as breast cancer cells, prostate cancer cells and bladder cancer cells. In addition, branched-chain fatty acids also have anti-inflammatory effects such as inhibition of neonatal necrotizing enterocolitis. Further analysis of branched-chain fatty acids in various foods and tissues of human body, and in-depth study on the structural function and mechanism of branched-chain fatty acids are important directions for the study of branched-chain fatty acids. |
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