Effects of ethanol extract of Rosa prickly seed on glucose metabolism of exhaustive exercise rats
  
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KeyWord:ethanol extract of Rosa prickly seed  exhaustive exercise  glucose metabolism  rat
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ZHANG Yuehua,MENG Qingyuan,GE Junying  
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Abstract:
      The effect of ethanol extract of Rosa prickly seed on glucose metabolism of exhaustive exercise rats were studied. Forty rats were divided into control group, low dose group(50 mg/kg), medium dose group(100 mg/kg) and high dose group(150 mg/kg). Rats were administrated with ethanol extract of Rosa prickly seed once a day and swam once a day for four weeks. The results showed that the blood sugar of rats in low, medium and high dose groups significantly increased compared with control group after experiment (p<0.05). The blood lactic acid contents of rats in low and midium dose groups significantly decreased compared with control group after experiment (p<0.05), especially the blood lactic acid content of rats in high dose group very significantly decreased compared with control group (p<0.01). The liver glycogen and muscle glycogen contents of rats in low, medium and high dose groups significantly increased (p<0.05). The blood sugar, liver glycogen and muscle glycogen contents of rats in each group after experiment reduced to different extent compared with that before experiment, while the blood lactic acid contents of rats in each group after experiment increased to different extent compared with that before experiment. The research suggested that the ethanol extract of Rosa prickly seed had a good effect on the glucose metabolism of exhaustive exercise rats.
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