In order to explore the protective effect of Idesia policarpa Maxim oil on myocardial mitochondria in rats after exhaustive exercise,fifty SD rats were randomly divided into control group, exhaustive exercise group, low, middle and high dose of Idesia policarpa Maxim oil groups. The control group did no exercise, and the exhaustive exercise group did run training.The low, middle and high dose groups were fed with Idesia policarpa Maxim oil 2 h after running. The training was performed for 6 weeks, 6 d a week and rested on Sunday. The results showed that ATP synthesis ability, SOD activity, GSH-Px activity and CAT activity in myocardial mitochondria of exhaustive exercise group were significantly lower than those of control group (P<0.05, P<0.01), Ca2+ content and MDA content were significantly higher than those of control group (P<0.05, P<0.01). The ATP synthesis ability, SOD activity, GSH-Px activity and CAT activity of low, middle and high dose of Idesia policarpa Maxim oil groups increased, while Ca2+ content and MDA content decreased. The ATP synthesis ability, SOD activity, GSH-Px activity, CAT activity, Ca 2+ content and MDA content of high dose of Idesia policarpa Maxim oil group had significant differences with the exhaustive exercise group (P<0.05, P<001).The results indicated that the Idesia policarpa Maxim oil had a good protective effect on myocardial mitochondria in rats after exhaustive exercise. |