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| Preparation and stability of Eucommia seed oil nanoemulsion by ultrasonic emulsification |
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| KeyWord:Eucommia seed oil nanoemulsion ultrasonic emulsification stability |
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| Abstract: |
| The Eucommia seed oil nanoemulsion was prepared by ultrasonic emulsification with Tween 80 as emulsifier. The effects of ultrasonic power, ultrasonic time, volume fraction of Eucommia seed oil and mass concentration of emulsifier on the average particle size of the nanoemulsion were studied. The preparation conditions of Eucommia seed oil nanoemulsion were optimized by response surface methodology and the stability was preliminarily evaluated. The results showed that the optimal conditions for preparing Eucommia seed oil nanoemulsion by ultrasonic emulsification were obtained as follows:ultrasonic time 5 min, ultrasonic power 432.47 W, volume fraction of Eucommia seed oil 7.62% and mass concentration of emulsifier 0.12 g/mL. Under these conditions, the average particle size of Eucommia seed oil nanoemulsion was (121.5±1.43) nm, and the absolute value of the Zeta potential was (28.6±0.35) mV. When the Eucommia seed oil nanoemulsion was stored for less than 20 d and below 25?℃, the absolute value of the Zeta potential of Eucommia seed oil nanoemulsion was 30-20 mV, and the average particle size was 100-150 nm, indicating that the Eucommia seed oil nanoemulsion prepared by ultrasonic emulsification had good storage stability. |
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