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| Establishment of nutritional evaluation model of albumin-based emulsions as potential delivery systems for oil to Caenorhabditis elegans |
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| DOI： |
| KeyWord:Caenorhabditis elegans albumin-based emulsion delivery system nutritional evaluation model oil |
| FundProject:国家自然科学基金（31872895）；国家食品科学与工程一流学科建设项目（JUFSTR20180202）；中国博士后科学基金资助项目（2017M621635） |
| Author Name | Affiliation | | YANG Jinyue, ZHANG Tao, CHANG Ming, LIU Ruijie,
JIN Qingzhe, WANG Xingguo | State Key Laboratory of Food Science and Technology, School of Food Science and Technology,
Jiangnan University, Wuxi 214122, Jiangsu, China |
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| Abstract: |
| Caenorhabditis elegans is an important model for studing diseases about lipid metabolism. Due to the water-soluble culture environment, it is difficult to disperse the oil evenly in the medium, which affects the intake of oil by Caenorhabditis elegans. The nutritional evaluation model of albumin-based emulsions for delivering oil to Caenorhabditis elegans was developed. The results showed that the emulsion could be ingested by Caenorhabditis elegans according to fluorescence labeling and fatty acid composition analysis. When the particle size of the emulsions was in the range of 200-400 nm, the intake of emulsions increased with the decrease of particle size. When the concentration of MCT was in the range of 0.01-10 mmol/L, the intake of emulsions increased with the MCT concentration increasing. |
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