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母乳脂肪在早产儿体外胃肠道消化特性研究 |
Digestive characteristics of breast milk fat in vitro simulated pre-term infants gastrointestinal digestion |
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DOI:10.12166/j.zgyz.1003-7969/2020.11.010 |
中文关键词: 母乳脂肪 早产儿 体外模拟消化 胃消化 小肠消化 脂解 |
英文关键词:breast milk fat pre-term infant in vitro simulated digestion gastric digestion small intestine digestion lipolysis |
基金项目::江南大学学生创新训练计划资助(2019522X); 中国科协青年人才托举工程(2017QNRC001) |
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中文摘要: |
建立体外模拟早产儿胃肠道消化动态模型,研究母乳脂肪在婴儿胃部和小肠环境的脂解特性。结果表明: 母乳脂肪在早产儿胃部消化速度缓慢,120 min时脂解程度为(7.03±0.15)%,在小肠环境中消化速度较快,120 min时脂解程度达到(37.22±1.43)%。母乳脂肪消化全期脂解产生的游离脂肪酸主要为C18∶ 1n-9、C18∶ 2n-6和C16∶ 0,在小肠阶段释放出的sn-2位甘油单酯的脂肪酸组成主要为C16∶ 0、C14∶ 0、C18∶ 1n-9和C18∶ 2n-6。 |
英文摘要: |
An in vitro dynamics model of pre-term infant gastrointestinal digestion was established to study the lipolytic properties of breast milk fat in the infant’s stomach and small intestine. The results showed that breast milk fat digested slowly in the stomach of pre-term infants, and the lipolysis degree was (7.03±0.15)% when digested for 120 min. The breast milk fat digested faster in the small intestine of pre-term infants, and the lipolysis degree was (37.22±1.43)% when digested for 120 min. The free fatty acids produced during the whole digestion phase were mainly C18∶ 1n-9, C18∶ 2n-6 and C16∶ 0, and the fatty acid composition of the monoglyceride at the sn-2 position released in the small intestine were mainly C16∶ 0, C14∶ 0, C18∶ 1n-9 and C18∶ 2n-6. |
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