| The flaxseed oil with the mass concentration of 0.15, 0.05, 0.025 g/mL was used as high, medium and low dose groups to give mice by intragastric administration with 10 mL/(kg·d) for 30 d, then the weight, ratio of organ weight to body weight (thymus index, spleen index), cellular immune function (mice lymphocyte transformation test, delayed type hypersensitivity test), humoral immune function (antibody-producing cell test, serum hemolysin determination test), monocytes-macrophages function (carbon clearance test, phagocytosis of peritoneal macrophages test) and NK cell activity were determined to investigate the effect of flaxseed oil on the immune function of mice. The results showed that flaxseed oil had no significant effect on the body weight, ratio of organ weight to body weight, serum hemolysin and monocytes-macrophages function of mice(P>0.05). Compared with the control group, the medium dose group and high dose group could significantly increase the cellular immune function (lymphocyte transformation, delayed type hypersensitivity) and NK cell activity (P<0.05). The results indicated that flaxseed oil had the function of enhancing immunity of mice. |
