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| Preparation and quality evaluation of peony seed oil nanoemulsion gel based on Bletilla striata polysaccharide |
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| DOI：10.12166/j.zgyz.1003-7969/2020.12.016 |
| KeyWord:peony seed oil Bletilla striata polysaccharide nanoemulsion gel quality evaluation |
| FundProject:西安医学院2018年配套基金项目（2018PT63）；陕西省教育厅科技计划项目（18JK0671）；陕西高校青年创新团队建设项目（陕教\[2019\]90号）；西安医学院2017年国家基金培育项目（2017GJFY10）；西安医学院2018年青年科研基金项目（2018QN12） |
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| Abstract: |
| The combined techniques of high speed shear-high pressure homogenization-ultrasonic were adopted to prepare the peony seed oil nanoemulsion, the Bletilla striata polysaccharide was crosslinked with carporated 940 to prepare gel, and the peony seed oil nanoemulsion was added into gel to prepare peony seed oil nanoemulsion gel, then the qualities of the peony seed oil nanoemulsion and nanoemulsion gel were evaluated. The results showed that the optimal formula of the peony seed oil nanoemulsions was obtained as follows: peony seed oil 0.9%, PEG-40 hydrogenated castor oil 1.8%, and PEG400 03%. The appearance of peony seed oil nanoemulsion showed translucent liquid and nattier blue opalescence,with the diameter of （88.44±1.74）nm, the Zeta potential of （-18.6±2.8）mV, the PDI of 0538±0.084, the conductivity of （8.27±011）μS/cm, and the viscosity of （4724±0.55）mPa·s. The peony seed oil nanoemulsion was stable at room temperature and after high speed centrifugation. The appearance of peony seed oil nanoemulsion gel showed tan,uniform exquisite and easy to spread, with the pH of 6.82±0.03, the viscosity of （53 829±146）mPa·s, the peony seed oil content of （2.60±0.03）mg/g, and had a good slow-release effect. The preparation of peony seed oil nanoemulsion gel was simple, and the research could provide a reference for application of peony seed oil in medicine and cosmetics. |
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