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薏苡仁油致突变性实验研究
Mutagenicity of coix seed oil
  
DOI：10.12166/j.zgyz.1003-7969/2020.06.014
中文关键词:  薏苡仁油  Ames试验  骨髓细胞微核试验  精子畸形试验  致突变性
英文关键词:coix seed oil  Ames test  bone marrow micronucleus test  sperm malformation test  mutagenicity
基金项目:福州市科技计划项目（2018-G-81）
Author NameAffiliation
HUANG Yangzeng 1. Research Center of Medicinal Mushroom Cultivation and Deep Processing of Local and National United Engineering, Fujian Xianzhilou Biological Science and Technology Co., Ltd., Fuzhou 350002,China
2. Fujian Center of Disease Control and Prevention, Fuzhou 350001,China 
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中文摘要:
      按照《保健食品检验与评价技术规范》，采用Ames试验、小鼠骨髓细胞微核试验和小鼠精子畸形试验研究薏苡仁油的致突变性。结果表明：Ames试验、小鼠骨髓细胞微核试验和小鼠精子畸形试验结果均为阴性。因此，在本试验条件下，薏苡仁油未显示有致突变性。
英文摘要:
      The mutagenicity of coix seed oil was studied by three mutagenicity tests including Ames test,bone marrow micronucleus test and sperm malformation test in mice in accordance with the terms from Technical Standards for Test & Assessment of Health Food. The results showed that in all three mutagenicity tests,no mutagenic effect was observed in any coix seed oil treated group.Therefore,coix seed oil had no mutagenic effect under the experimental conditions.
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