| α-Linolenic acid is an n-3 series unsaturated fatty acid, which has functions of reducing blood lipid and blood pressure, improving cardiovascular disease, improving memory, protecting nerve tissue, preventing allergic diseases, inhibiting tumor cell metastasis and delaying aging. The separation and purification technologies mainly included urea adduction fractionation, freezing crystallization, molecular distillation, silver ion complexation, column chromatography and β-cyclodextrin adduction and combined method. The research progress on separation and purification technology of α-linolenic acid was reviewed,and the principles, advantages and disadvantages of various separation and purification technologies were summarized.From the existing research results, it could be seen that a single separation and purification method was difficult to obtain high purity α-linolenic acid due to its own disadvantages, while the combination of two or more separation and purification techniques was an effective way to obtain high purity α-linolenic acid. |
