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| α-亚麻酸分离纯化技术研究进展 |
| Progress on separation and purification technology of α-linolenic acid |
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| DOI：10.12166/j.zgyz.1003-7969/2020.08.007 |
| 中文关键词: α-亚麻酸 分离纯化 研究进展 |
| 英文关键词:α-linolenic acid seperation and purification research progress |
| 基金项目:陕西省2018年重点研发计划项目（2018NY-130 |
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| 中文摘要: |
| α-亚麻酸属n-3系不饱和脂肪酸，具有降低血脂血压、改善心血管疾病、提高记忆力、保护神经组织、预防过敏性疾病、抑制肿瘤细胞转移、延缓衰老等功能。目前，α-亚麻酸的分离纯化方法主要有尿素包合法、低温冷冻结晶法、分子蒸馏法、银离子络合法、柱层析法、β-环糊精包合法及耦合法。综述了α-亚麻酸分离纯化技术的研究进展，总结了各种分离纯化方法的原理及优缺点。从现有的研究结果可看出，单一的分离纯化方法由于其各自的弊端很难得到高纯度的α-亚麻酸，采用两种及两种以上分离纯化技术耦合是获得高纯度α-亚麻酸的有效途径。 |
| 英文摘要: |
| α-Linolenic acid is an n-3 series unsaturated fatty acid, which has functions of reducing blood lipid and blood pressure, improving cardiovascular disease, improving memory, protecting nerve tissue, preventing allergic diseases, inhibiting tumor cell metastasis and delaying aging. The separation and purification technologies mainly included urea adduction fractionation, freezing crystallization, molecular distillation, silver ion complexation, column chromatography and β-cyclodextrin adduction and combined method. The research progress on separation and purification technology of α-linolenic acid was reviewed,and the principles, advantages and disadvantages of various separation and purification technologies were summarized.From the existing research results, it could be seen that a single separation and purification method was difficult to obtain high purity α-linolenic acid due to its own disadvantages, while the combination of two or more separation and purification techniques was an effective way to obtain high purity α-linolenic acid. |
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