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| 核桃油中亚麻酸对小鼠血脂和肝功能的影响 |
| Effects of linolenic acid prepared from walnut oil on blood lipid and liver function in mice |
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| DOI：10.12166/j.zgyz.1003-7969/2020.08.011 |
| 中文关键词: 核桃油 亚麻酸 血脂；肝功能 |
| 英文关键词:walnut oil linolenic acid blood lipid liver function |
| 基金项目:：陕西省重点研发计划项目（2018TSCXL-NY-06-02）；陕西省农业科技驱动项目（NYKJ-2018-XA-06）；中央高校基本科研业务费资助项目（GK201806002） |
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| 中文摘要: |
| 以纯度为97.2%的冷榨核桃油亚麻酸为原料，研究其对小鼠血脂和肝功能的影响。将110只雄性昆明小鼠随机分为11组，分别灌胃核桃油、亚麻酸、花生油30 d，测定小鼠血脂和肝脏指标。结果表明：亚麻酸可降低高脂血症小鼠体重、血清总胆固醇（TC）、低密度脂蛋白胆固醇（LDL-C）、甘油三酯（TG）、肝脏质量和肝脏系数，可提高小鼠血液高密度脂蛋白胆固醇（HDL-C）水平。研究表明核桃油中亚麻酸防治小鼠高脂血症和动脉粥样硬化症作用显著，且优于核桃油和花生油。 |
| 英文摘要: |
| The effects of linolenic acid with purity of 97.2% prepared from cold-pressed walnut oil on blood lipid and liver function in mice were evaluated. 110 male kunming mice were randomly divided into eleven groups and fed with walnut oil, linolenic acid and peanut oil for 30 d,then the indexes of blood lipid and liver of mice were determined. The results showed that the linolenic acid prepared by walnut oil could reduced the body weight, serum total cholesterol(TC), low-density lipoprotein(LDL-C), triglyceride(TG), liver weight and liver coefficient, while improve the level of high-density lipoprotein(HDL-C) in blood of mice. The effect of linolenic acid prepared from walnut oil on hyperlipidemia and atherosclerosis in mice was significant,and was better than walnut oil and peanut oil. |
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