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| Effect of yak butter and yak butter phospholipids on lipid metabolism in C57BL/6J mice |
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| DOI： |
| KeyWord:yak butter yak butter phospholipids fatty acid blood lipid blood sugar |
| FundProject:青海省科技厅项目(2018-ZJ-728) |
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| Abstract: |
| The SPF C57BL/6J mice were randomly divided into five groups:control group, yellow butter group, white butter group, yellow butter phospholipid group and white butter phospholipid group.Yak butter and yak butter phospholipids were fed to mice. After one month and five months of feeding, serum total cholesterol (TC), triglycerides (TG), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C) and blood sugar levels were measured, and liver pathological observations and adipose fatty acid composition were analyzed. The results showed that long-term feeding of yak butter could increase the weight of mice, while mice fed with yak butter phospholipid gained less weight. With the prolonging of feeding time in each experimental group, serum HLD-C levels in mice improved. The serum TC, TG, LDL-C and blood sugar levels in mice of butter group were the highest, followed by phospholipid group and control group. After one month of feeding, the liver and abdominal fat structure of each group of mice was normal and complete, no obvious tissue lesions were observed. After five months of feeding, compared with the control group, different degrees of inflammatory cell immersion and lipid deposition were observed in yellow butter group, white butter group, yellow butter phospholipid group and white butter phospholipid group. Compared with feeding for one month, after five months of feeding, yak butter phospholipids could increase the unsaturated fatty acids content in adipose tissue of mice. Compared with control group, yak butter and yak butter phospholipids could increase the branched chain fatty acids content in adipose tissue of mice. |
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