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| 呋喃脂肪酸的来源与功能研究进展 |
| Advance in the resource and function of furan fatty acids |
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| DOI： |
| 中文关键词: 呋喃脂肪酸；抗氧化；3-羧基-4-甲基-5-丙基-2-呋喃丙酸 来源 功能 |
| 英文关键词:furan fatty acids antioxidation 3-carboxy-4-methyl-5-propyl-2-furanpropanoic acid resource function |
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| 中文摘要: |
| 呋喃脂肪酸是一组以呋喃环为主体的特殊脂肪酸，多存在于微生物、植物及鱼类中。研究表明，呋喃脂肪酸可以有效地清除活性氧自由基，并且减缓氧化胁迫诱导的损伤。然而，呋喃脂肪酸代谢产物3-羧基-4-甲基-5-丙基-2-呋喃丙酸对糖尿病及慢性肾病病情进展的作用仍存在争议。进一步深入研究呋喃脂肪酸的结构与生理功能，是目前呋喃脂肪酸研究的重要方向。对呋喃脂肪酸的来源、合成代谢及对人体的生理效应研究进展进行综述，为呋喃脂肪酸及其产物的后续研究提供参考。 |
| 英文摘要: |
| As a class of special fatty acids with a furan moiety in the central part, furan fatty acids (F-acids) are mainly found in microorganisms, plants and fish. Recent studies have showed that F-acids can effectively scavenge reactive oxygen free radicals, and alleviate oxidative stress-induced damage. However, the relationships of one metabolite of F-acids, 3-carboxy-4-methyl-5-propyl-2-furanpropanoic acid (CMPF), with diabetes and chronic kidney disease remain controversial. Further investigation on the structure and physiological function of F-acids is a critical direction for the study of F-acids. The research progress on the source, synthesis and physiological functions of furan fatty acids were summarized to provide reference for the further research on F-acids and their products. |
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