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Extraction and separation of flavonoids from Ginkgo biloba leaves
  
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KeyWord:Ginkgo biloba leaves  flavonoids  extraction  membrane separation  gradient membrane
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LI Zhiping Shaanxi Hanwang Pharmaceutical Co., Ltd.,Hanzhong 723000,Shaanxi,China 
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Abstract:
      The ethanol extraction and membrane separation process of flavonoids from Ginkgo biloba leaves were studied, and the process conditions were optimized as follows: extracting Ginkgo biloba leaves for 2 h at 80 ℃ and ratio of material to solvent 1∶ 10 with 70% ethanol, then separated and purified by a gradient membrane device composed of ceramic membranes with relative molecular weights of 30 000, 10 000 and 5 000 under the conditions of the pressure 0.25 MPa, temperature 30 ℃ and time 120 min, and the flavonoid transmission rate was 94.22%, and the content of flavonoids in the product was 4560% after membrane separation.
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