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| Supercritical CO2 extraction of okra seed oil and preparation of its soft capsule |
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| DOI： |
| KeyWord:okra seed oil supercritical CO2 extraction soft capsule preparation process optimization |
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| Abstract: |
| Taking the oil extraction rate of okra seed as the response value, the response surface methodology was used to optimize the supercritical CO2 extraction process of okra seed oil.Taking the disintegration time as the evaluation index, the preparation of okra seed oil soft capsule was optimized by orthogonal experiment. Th results showed that the optimal supercritical CO2 extraction conditions of okra seed oil were obtained as follows: extraction pressure 30 MPa, extraction temperature 60?℃, extraction time 60 min, and under these conditions, the oil extraction rate was 17.23%. The optimal preparation process of okra seed oil soft capsule were obtained as follows: mass ratio of water to gelatin 1∶?1, mass ratio of gelatin to glycerin 3∶?1, sol temperature 80?℃, sol time 10 h, and under these conditions, the disintegration time of the okra seed oil soft capsule was 30.3 min,which met the requirement of disintegration time not longer than 1 h of soft capsule in Chinese Pharmacopoeia. |
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