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| Meta-analysis of the effect of flaxseed diet on blood pressure and BMI in patients with hypertension |
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| DOI： |
| KeyWord:flaxseed hypertension BMI Meta analysis |
| FundProject:吉林省科技厅项目（20200403114SF） |
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| Abstract: |
| The included literature was screened by searching for randomized controlled trials that met the inclusion and exclusion criteria in domestic and international databases, the quality of the included literature was evaluated using the risk of bias evaluation criteria of the Cochrane collaboration, and the extracted data were subjected to Meta analysis using CMA3.3 software to explore the effect of flaxseed diets on blood pressure and BMI in patients with hypertension. Finally, 8 articles were included. Meta analysis results showed that flaxseed diet could effectively reduce blood pressure and BMI, and the combined effect was statistically significant, SBP\[WMD=-4.209，95%CI（-8.214，-0.203），P=0039\], DBP\[WMD=-2.988，95%CI（-4.691，-1.284），P=0.001\], BMI\[WMD=-0.748，95%CI（-1.275，-0.221），P=0.005\]. The combined effect of consumption for more than 12 weeks was statistically significant, SBP\[WMD=-7.365，95%CI（-10.847，-3.883）, P<0.001\], DBP\[WMD=-3.488，95%CI（-5.486，-1.410），P=0.001\], BMI\[WMD=-0.780, 95%CI（-1.510，-0.049）, P=0.036\]. The combined effect of consuming 10-30 g of flaxseed a day was statistically significant, SBP\[WMD=-6.983，95%CI（-10.438，-3.528），P<0.001\], DBP\[WMD=-4.505，95%CI（-6.726，-2.284），P<0.001\], BMI\[WMD=-0.728，95%CI（-1.453，-0.004）, P=0.049\]. Therefore, continuous consumption for more than 12 weeks and daily consumption of 10-30 g flaxseed diet could effectively reduce blood pressure and BMI in patients with hypertension. |
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