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| 亚麻籽膳食对高血压患者血压 和BMI影响的Meta分析 |
| Meta-analysis of the effect of flaxseed diet on blood pressure and BMI in patients with hypertension |
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| DOI： |
| 中文关键词: 亚麻籽 高血压 BMI Meta分析 |
| 英文关键词:flaxseed hypertension BMI Meta analysis |
| 基金项目:吉林省科技厅项目（20200403114SF） |
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| 中文摘要: |
| 通过检索国内外数据库中符合纳入、排除标准的随机对照试验，筛选纳入的文献，采用Cochrane协作组的偏倚风险评价方法对纳入的文献进行质量评价，并使用CMA3.3软件对提取的数据进行Meta分析，探讨亚麻籽膳食对高血压患者血压和BMI影响的效果。结果最终纳入8篇文献，Meta分析结果显示：亚麻籽膳食能有效降低血压和BMI，合并效应具有统计学意义，SBP\[WMD=-4.209，95%CI（-8.214，-0.203），P=0.039\]、DBP\[WMD=-2.988，95%CI（-4691，-1.284），P=0.001\]、BMI\[WMD=-0.748，95%CI（-1.275，-0.221），P=0.005\]；食用时间12周以上合并效应具有统计学意义，SBP\[WMD=-7.365，95%CI（-10.847，-3.883），P<0.001\]、DBP\[WMD=-3.488，95%CI（-5.486，-1.410），P=0.001\]、BMI\[WMD=-0.780，95%CI（-1.510，-0.049）,P=0.036\]；每天食用亚麻籽10～30 g合并效应具有统计学意义，SBP\[WMD=-6.983，95%CI（-10.438，-3.528），P<0.001\]、DBP\[WMD=-4.505，95%CI（-6.726，-2.284），P<0.001\]、BMI\[WMD=-0.728，95%CI（-1.453，-0.004）,P=0.049\]。因此，持续食用12周以上，每日食用10～30 g亚麻籽膳食能够有效降低高血压患者的血压和BMI。 |
| 英文摘要: |
| The included literature was screened by searching for randomized controlled trials that met the inclusion and exclusion criteria in domestic and international databases, the quality of the included literature was evaluated using the risk of bias evaluation criteria of the Cochrane collaboration, and the extracted data were subjected to Meta analysis using CMA3.3 software to explore the effect of flaxseed diets on blood pressure and BMI in patients with hypertension. Finally, 8 articles were included. Meta analysis results showed that flaxseed diet could effectively reduce blood pressure and BMI, and the combined effect was statistically significant, SBP\[WMD=-4.209，95%CI（-8.214，-0.203），P=0039\], DBP\[WMD=-2.988，95%CI（-4.691，-1.284），P=0.001\], BMI\[WMD=-0.748，95%CI（-1.275，-0.221），P=0.005\]. The combined effect of consumption for more than 12 weeks was statistically significant, SBP\[WMD=-7.365，95%CI（-10.847，-3.883）, P<0.001\], DBP\[WMD=-3.488，95%CI（-5.486，-1.410），P=0.001\], BMI\[WMD=-0.780, 95%CI（-1.510，-0.049）, P=0.036\]. The combined effect of consuming 10-30 g of flaxseed a day was statistically significant, SBP\[WMD=-6.983，95%CI（-10.438，-3.528），P<0.001\], DBP\[WMD=-4.505，95%CI（-6.726，-2.284），P<0.001\], BMI\[WMD=-0.728，95%CI（-1.453，-0.004）, P=0.049\]. Therefore, continuous consumption for more than 12 weeks and daily consumption of 10-30 g flaxseed diet could effectively reduce blood pressure and BMI in patients with hypertension. |
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