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| Polyphenols content, antioxidant and hypoglycemic activities of Fengdan seed ethanol extract from different producing areas |
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| DOI： |
| KeyWord:Fengdan seed different producing areas polyphenols antioxidant activity hypoglycemic activity |
| FundProject:西安市科技局项目（2020KJRC0135）；西安医学院配套基金项目（2018PT61）；西安医学院校级重点药学学科项目（西安发\[2019\]96号） |
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| Abstract: |
| ：Fengdan seeds from four producing areas(Baoji(Shaanxi), Heze(Shandong), Bozhou(Anhui), Tongling(Anhui)) were used as the research objects, the polyphenols content of Fengdan seed ethanol extract was determined by Folin-Ciocalteu method.The antioxidant activity of the extract was evaluated by DPPH and ABTS+ radical scavenging experiments,and the hypoglycemic activity was evaluated by studying the inhibitory effect on α-glycosidase enzymes. Finally, the polyphenols compounds in the Fengdan seed extract with the best activity were analyzed by LC-MS/MS-HESI. The results showed that the content of polyphenols in Fengdan seed extract from Tongling, Anhui was the highest (40.69 mg/g).The Fengdan seed extracts from four producing areas had certain antioxidant and hypoglycemic activities, and the activity of Fengdan seed extract from Tongling, Anhui was the best, followed by Bozhou (Anhui), Heze (Shandong) and Baoji (Shaanxi). A total of 24 polyphenols compounds were identified from Fengdan seed extract from Tongling, Anhui. The polyphenols content, antioxidant and hypoglycemic activities of Fengdan seed extract from Tongling, Anhui were better than those of the other three producing areas, and had a good application prospect. |
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