Progress in fat reduction of conjugated linoleic acid and its molecular mechanism
  
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KeyWord:conjugated linoleic acid  weight loss and fat reduction  molecular mechanism
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LI Hailing School of Pharmaceutical Science, Sun Yat-Sen University, Guangzhou 510006, China
 
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Abstract:
      Conjugated linoleic acid, a mixture of eighteen carbon polyunsaturated fatty acid with conjugated double bonds, has many activities in weight loss and fat reduction of the body and verifiable clinical safety, which makes it become one of the hotspots among the international market of losing weight. The research results on weight loss and fat reduction of conjugated linoleic acid was briefly introduced, and the mechanisms on weight loss and fat reduction was summarized from 6 aspects of regulating energy metabolism, lipid metabolism, skeletal muscle metabolism, glucose metabolism, mediating adipocyte differentiation and apoptosis and intestinal microflora, also the existing problems and future opportunity were reviewed and discussed. As a natural product used to lose weight and reduce fat, conjugated linoleic acid has a greater and broader development potential.
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