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| Advance in potential anti-cancer effect and mechanism of saturated fatty acids |
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| DOI： |
| KeyWord:saturated fatty acid anti-cancer effect mechanism |
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| Abstract: |
| Dietary saturated fatty acids (SFAs) is usually associated with negative consequences for human health. However, there are some contradictory experimental results on the physiological effects and biological functions of various SFAs. The anti-cancer effects and mechanisms of SFAs were mainly summarized and discussed, so as to provide the way for adjuvant therapy of cancer. At present, there are many reports on the anti-cancer effects of short-chain SFAs, medium-chain SFAs, odd-chain SFAs and branched-chain SFAs, SFAs exert anti-cancer effects mainly by blocking the cell cycle, inducing apoptosis, inhibiting cell migration and regulating cell growth-related signalling pathways, and affecting the expression of related genes and the phosphorylation levels of transcription factors. |
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