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| Progress on separation and purification technology of linoleic acid |
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| KeyWord:linoleic acid separation and purification research progress |
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| Abstract: |
| Linoleic acid，which belongs to an omega-6 type polyunsaturated fatty acid, possesses unique physiological functions and is closely associated with human health. Linoleic acid mostly originates from natural animal fats and vegetable oils, and its content cannot meet the needs of the food and pharmaceutical industries. Therefore, developing effective technologies for the separation and purification of linoleic acid has become a research hotspot in recent years. In order to provide a reference for the separation and purification of linoleic acid, the separation and purification technologies of linoleic acid at home and abroad in recent years were reviewed, the separation principle and research results of the methods of urea adduction fractionation, silver nitrate impregnated-silica gel column chromatography, molecular distillation, lipase hydrolysis, solvent freezing crystallization, high-speed countercurrent chromatography and integration were systematically introduced, and both the pros and cons of each separation and purification method were analyzed. The integration of two or more separation and purification technologies can complement mutual advantage and improve separation efficiency. Moreover, starch, melamine complexation method and pH zone refined countercurrent chromatography are worthy of further research. |
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