| In order to develop new technologies for industrial preparation of nanoemulsion, the effects of introducing micro-nano bubbles in the trough ultrasonic reactor on the intensity and distribution of the sound field were analyzed through simulation experiment. With peanut oil as oil phase, Tween 80 and Span 80 as emulsifiers, and nanoemulsion was prepared in trough ultrasonic reactor based on micro-nano bubble strengthening in the emulsification process. The effects of ultrasonic time, air intake, dosage of compound emulsifier on the average particle size and polydispersity index of nanoemulsion were investigated by orthogonal experiment, and the preparation conditions of nanoemulsion were optimized. The results showed that adding an appropriate amount of micro-nano bubbles could improve the sound field intensity and uniformity of distribution. The optimal conditions for preparation of nanoemulsion were obtained as follows: ultrasonic time 12 min, air intake 150 mL/min, dosage of compound emulsifier 3%(based on the water volume). Under these conditions, the average particle size of the nanoemulsion was 190.9 nm, and the polydispersity index was 0.178. The average particle size of the nanoemulsion was reduced by 73.3% than that without micro-nano bubble, and showed better dynamic stability. The average particle size and polydispersity index of the nanoemulsion prepared by this method are small, and the method has advantages of rapid preparation, large volume, and low cost. |
