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| Research status of polyunsaturated fatty acid in the intervention of alopecia and its mechanism of action |
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| DOI： |
| KeyWord:Omega-3 polyunsaturated fatty acids Omega-6 polyunsaturated fatty acids hair follicle alopecia cell growth factors |
| FundProject:广东省基础与应用基础研究基金（2021A1515012557） |
| Author Name | Affiliation | | ZOU Kuangyue1, YING Ming1,2, SUN Zhaojun3, XIONG Ying4,
WU Bo4, YANG Xuewei1,2 | 1.College of Life Science and Oceanography, Shenzhen University, Shengzhen 518000, Guangdong, China
2.Inova Bay Technology Co. , Ltd. , Shengzhen 518000, Guangdong, China
3.Shenzhen People′s Hospital
(Affiliated 1st Hospital of Southern University of Science and Technology), Shengzhen 518000,
Guangdong, China
4.Shenzhen Maternal and Child Health Care Hospital,
Shengzhen 518000, Guangdong, China |
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| Abstract: |
| Alopecia is one of the common diseases in dermatology, with a high incidence but limited clinical treatment. Most alopecia are associated with changes in hair follicle cycle, and Omega-3 and Omega-6 polyunsaturated fatty acids have been shown to promote or inhibit the release of signaling molecules by hair follicle cells to promote hair follicle growth, improve hair follicle cycle, and promote the regeneration of hair follicles. The research status of polyunsaturated fatty acids in the intervention of alopecia and the intervention mechanism were reviewed. It is expected to provide new ideas for the treatment of various types of alopecia by polyunsaturated fatty acids and to explore the treatment methods and mechanisms of alopecia,and to provide a theoretical basis for the improvement of alopecia by modern molecular biotechnology. |
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