Contamination status and dietary exposure assessment of aflatoxin B1 in peanut and its products sold in Shandong province
  
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KeyWord:aflatoxin B1  peanut  peanut butter  peanut oil  food contamination  exposure risk assessment
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DONG Wenya1, CHEN Chen1, ZHAO Xiulan1, YANG Yonghao1, ZHAO Jinshan2, XIAO Peirui2, CHU Zunhua2 1.School of Public Health, Shandong University, Jinan 250012, China
2.Shandong Center for Disease Control and Prevention, Institute of Preventive Medicine, Shandong University, Jinan 250014, China 
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Abstract:
      To investigate the contamination status of aflatoxin B1(AFB1) in peanut and its products sold in Shandong province, evaluate its exposure level and health risk, and provide basis for relevant departments to take control measures, a total of 246 peanuts,peanut butter and peanut oil were randomly collected from production and circulation links (farmers′markets and stores) in 16 cities of Shandong province from 2015 to 2020. The contents of AFB1 in peanut and its products were determined by high performance liquid chromatography-post-column derivatization method,and mean dietary exposure and margin of exposure (MOE) were calculated to evaluate the dietary exposure risk of residents to AFB1 through peanut and its products sold in Shandong province. The results showed that the total detection rate of AFB1 in peanut and its products was 28.46% and the unqualified rate was 772%. The detection rate of AFB1 in peanut butter and peanut oil was significantly higher than that in peanut. The detection rate of AFB1 in bulk peanut butter and peanut oil was significantly higher than that in pre-packing products. The AFB1 exposure of general consumption residents through peanut, peanut butter and peanut oil were 0.01, 0.61 ng/(kg·d)and 1.09 ng/(kg·d), the risk of liver cancer were 0.000, 0.019 and 0.034 cases per 100 000 people, and the MOE values were 30 500, 500 and 280, respectively. The AFB1 exposure of high consumption residents through peanut, peanut butter and peanut oil were 0.23, 6.64 ng/(kg·d)and 8.90 ng/(kg·d), respectively, the risk of liver cancer were 0.007, 0.205 and 0.274 cases per 100 000 people, and the MOE values were 1 326, 46 and 34, respectively. After strict implementation of the limit standard, AFB1 exposure and the risk of liver cancer were reduced by more than 50%. For greater protection of population health, it is necessary to take effective regulatory and risk management measures to control the AFB1 content in peanut and its products sold in Shandong province, especially in bu
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