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| Progress in the impact of medium-chain triglyceride in Alzheimer′s disease |
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| DOI： |
| KeyWord:medium-chain triglyceride Alzheimer′s disease antioxidant anti-inflammation reduction of brain amyloid-β deposition |
| FundProject:吉林省教育厅“十三五”科学技术项目（JJKH2020-0532KJ） |
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| Abstract: |
| In order to investigate the effectiveness of medium-chain triglyceride (MCT) in delaying the occurrence of Alzheimer′s disease (AD), the metabolic process of MCT in vivo was analysed, the action mechanism of MCT on AD was reviewed, and the application status of MCT foods for AD was presented. MCT may delay the occurrence of AD through antioxidant effects, anti-inflammatory effects, reduction of brain amyloid-β deposition, protection of mitochondrial function and improvement of brain energy metabolism. MCT has been used to alleviate the condition of patients with AD, such as Axona (composed of MCT) and Ketonformula (a milk powder based on MCT), etc. MCT has been shown a beneficial effect on AD, and can be used in the daily diet to delay the occurrence of AD. |
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