Research progress in physiological function and preparation method of conjugated linolenic acid
  
DOI:
KeyWord:conjugated linolenic acid  physiological function  preparation method  health products
FundProject:国家重点研发计划项目(2018YFD0901103);国家自然科学基金(42176242)
Author NameAffiliation
BAO Yating1, ZHAO Yaoyao2, ZHENG Zhou1, MIAO Jinlai1 1.First Institute of Oceanography, Ministry of Natural Resource, Qingdao 266061, Shandong, China
2.School of Basic Medicine, Qingdao University, Qingdao 266071 Shandong, China 
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Abstract:
      In order to provide scientific theoretical reference for the application of conjugated linolenic acid (CLNA) in the fields of functional foods, health products and medicines, the physiological function and preparation method of CLNA were reviewed.CLNA has a variety of physiological functions such as anti-cancer, regulating lipid metabolism, anti-inflammatory, anti-oxidation, anti-diabetic and so on. CLNA has great potential in the prevention and treatment of many common diseases, especially diabetes, obesity, and common cancers such as breast cancer and colon cancer. The extraction rate of CLNA prepared by physical extraction method is low, and it is not suitable for large-scale production in industry. Due to the need of substrates and catalysts, the subsequent purification step of the preparation of CLNA by chemical synthesis method is cumbersome. The microbial method and genetic engineering method can obtain a higher content of CLNA, so it has a good prospect for development.
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