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| Research progress on nutritional properties of Antarctic krill oil and its improvement on osteoporosis |
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| DOI： |
| KeyWord:Antarctic krill oil lipid lipid concomitant n-3 polyunsaturated fatty acid osteoporosis |
| FundProject:重庆市首批公共卫生重点学科（理化与卫生毒理）建设项目 |
| Author Name | Affiliation | | HU Zicong1,2,3, YANG Kejun4, FANG Cuilan5 | (1.Southern Zhejiang Key Laboratory of Crop Breeding, Wenzhou Academy of Agricultural Science, Wenzhou
325006, Zhejiang, China
2.College of Food Science, Southwest University, Chongqing 400715, China
3.Institute of Food Science, Wenzhou Academy of Agricultural Science, Wenzhou 325006, Zhejiang, China
4.Orthopedic Hospital Affiliated to Wenzhou Medical University, Wenzhou 325027, Zhejiang, China
5.Centre for Disease Control and Prevention of Jiulongpo, Chongqing 400039, China) |
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| Abstract: |
| Antarctic krill oil (AKO) is a novel marine functional lipid. In order to promote the clinical application of AKO, the nutritional composition of AKO was summarized, the mechanism of AKO in improving osteoporosis was described, and the future key work was prospected. AKO is rich in phospholipids, n-3 polyunsaturated fatty acids (n-3 PUFA), astaxanthin, α-tocopherol, and other bioactive factors. There are three mechanisms for AKO to improve osteoporosis, namely, inhibiting osteoclastogenesis, promoting osteoblastogenesis, and regulating bone marrow mesenchymal stem cells. Future in-depth investigations into AKO should focus on large-scale clinical trials, standardized dosages, and long-term efficacy validation. |
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