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Advances in transcriptional regulation of lipid synthesis in microalgae |
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DOI: |
KeyWord:microalgae transcription factors transcription regulation lipid accumulation |
FundProject:辽宁省教育厅2020年度科研项目(J2020113);辽宁省市场监督管理局2022年度市场监管科技计划项目(2022ZC025) |
Author Name | Affiliation | ZHANG Yibo1, XUE Yongchang1, LIU Changbin1,2 | (1.School of Biological Engineering, Dalian Polytechnic University,Dalian 116034, Liaoning, China
2.Instrumental Analysis Center, Dalian Polytechnic University, Dalian 116034, Liaoning, China ) |
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Abstract: |
Biofuel is an ideal alternative to traditional fossil fuels, and microalgae is excellent raw materials for the production of biofuels. Through the understanding of the synthesis and regulation of microalgae lipid, the production efficiency of biodiesel by microalgae can be effectively improved. Transcription factors are protein molecules with special functional structures that perform the function of regulating gene expression. In the complex lipid synthesis and metabolism process, transcription factors can collectively regulate multiple enzyme lines in the metabolic process, thus promoting lipid accumulation in algal cells. The synthesis pathway of microalgae lipid was introduced, the key enzymes in the synthesis pathway were briefly introduced, and the regulation effect of bZIP, MYB, Dof and bHLH transcription factors on the microalgae lipid synthesis was reviewed. Microalgae lipid synthesis involves multiple pathways of multiple subcellular units, and is a very complex metabolic network process, and changing the expression of related enzymes in the synthetic pathways by genetic engineering means can increase lipid accumulation in microalgae. |
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