| In order to provide reference for the research and development of health care products with animal and plant derived lipids, the mixed hyperlipidemia animal model of SD rats was established by the high-fat diet, and the effects of the combination of egg yolk phospholipid and perilla seed oil on blood lipid health level was revealed. 50 Male SD rats were divided into blank control group, model control group, high, medium and low dose groups of combination of egg yolk phospholipid and perilla seed oil, and the changes of body weight, liver index, blood lipid level, body composition and liver lipid droplet content in rats were analyzed. The results showed that after 45 d of administration of the test substance, the body weight of the rats in each group did not change significantly, but the liver index of the medium and high dose groups, the TC levels in each dose group, and the TG levels in the high dose group were significantly lower than those in the model control group. There was a significant dose-effect relationship between the decreasing trend of TC and TG levels and the dose of the test substance, while there was no significant change in HDL-C and LDL-C levels in each dose group. The proportion of body fat in the body composition of rats in each dose group decreased compared with the model control group, and the proportion of lean body mass increased, but there was no significant difference between them. The content of liver lipid droplets in each dose group was very significantly lower than that in the model control group. In summary, the combination of egg yolk phospholipid and perilla seed oil is helpful in maintaining the healthy blood lipid level of rats. |
