Progress on the preparation, bioactivity and structure-activity relationship of selenium-enriched bioactive peptides
  
DOI:10.19902/j.cnki.zgyz.1003-7969.230301
KeyWord:selenium-enrichment  bioactive peptides  preparation method  bioactivity  structure-activity relationship
FundProject:河南省科技研发计划联合基金(应用攻关类)(232103810064);河南省重点研发专项(231111111800);国家自然科学基金(32202079);国家自然科学基金(联合基金)重点项目(U21A20270);河南省重点研发与推广专项(科技攻关)(222102110112);河南工业大学创新基金支持计划专项资助(2021ZKCJ03);河南工业大学青年骨干教师培育计划(21421237)
Author NameAffiliation
HOU Chunyan, YANG Chenxian (College of Food Science and Engineering, Henan University of Technology, Zhengzhou 450001, China) 
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Abstract:
      Selenium is an essential trace nutritional element that is very important for human life activities. Aiming to provide a theoretical basis for the research and application of selenium-enriched bioactive peptides, the raw material sources, preparation methods, bioactivities of selenium-enriched bioactive peptides were summarized. The research progress on selenium and peptides binding modes as well as the structure-activity relationship of selenium-enriched bioactive peptides were elaborated. The raw materials of selenium-enriched bioactive peptides mainly come from the transformation of biocarriers, such as plant sources, animal sources, and microbial sources.The selenium-enriched bioactive peptides can be prepared by enzymatic hydrolysis and microbial fermentation methods, which have a wide range of bioactivities, such as antioxidant, anti-fatigue, blood pressure lowering, anti-inflammatory, and so on. The bioactivities of selenium-enriched bioactive peptides are the results of the joint action of selenium and peptides, which are closely related to the sequence, spatial structure and interaction force of amino acids, but their structure-activity relationships need to be further studied.
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