Research progress on the mechanism of diacylglycerol on reducing blood lipid and controlling body weight
  
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KeyWord:diacylglycerol  blood lipid reduction  body weight control  antiobesity  mechanism
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Author NameAffiliation
SHI Lina1,WANG Yaqun2,WANG Mingxing2,WANG Yuehua2,CHENG Fangyuan2, JIN Jun1,JIN Qingzhe1,WU Gangcheng1,WANG Xingguo1 1.School of Food Science and TechnologyJiangnan UniversityWuxi 214122JiangsuChina 2.Changshouhua Food Company LimitedBinzhou 256209ShandongChina 
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Abstract:
      Diacylglycerol (DAG) is an ester formed by the substitution of a fatty acid by a hydroxyl group in triglycerides, and it is one of the natural components of dietary fats and oils. In order to provide a theoretical reference for the application of DAG oil as a functional blood lipid-lowering and weight-reducing oil, the blood lipid reduction and body weight control efficacy of DAG were introduced, and the mechanism of action was reviewed. DAG has different digestive properties from TAG due to its own specific structure, and DAG can up-regulate the expression of fat oxidation and thermogenesis genes in the small intestine, the expression of genes related to β-oxidation in the liver, inhibit lipid transport and enhance plasma lipid clearance. In conclusion, based on the specific digestive and metabolic pathways of DAG and the regulation of lipid metabolism-related genes after DAG intake, DAG can effectively reduce the postprandial lipid level and the accumulation of body fat to achieve the effect of controlling body weight and improving or preventing the occurrence of obesity.
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